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Biologics

The infinite Monkey Cage

To provide some diversion during these trying times, a colleague recommended ‘The infinite Monkey Cage’. Extremely funny British science podcast. There are more than 10 seasons for your pleasure. You will learn and you will laugh. If you like Monty Python you are on...

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COVID-19 vaccines

Hope for containing the COVI-19 pandemic rests on the develop of an effective vaccine for SARS-CoV-2. Recently we found an interesting list of 16 ongoing efforts to develop a SARS-CoV-2 vaccine in the magazine The Scientist. These vaccines vary considerably in their...

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Phage to prevent virus infection

Another potential application for phage that could not be more timely: phage-based particles engineered to envelop virus and prevent virus entry into mammalian cells. A team in Germany and Norway developed modified phage capsid that display sugar moieties to bind...

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Who’s afraid of IgM?

Immunoglobulin M (IgM) is the second most common antibody in humans surpassed only by immunoglobulin G (IgG). The IgM molecule is a pentamer - whereas IgG is a dimer - and with a molecular weight of appr. 900,000 D IgM has more than 5 times the molecular weight of...

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Monoclonals for migraine

Exciting news regarding a new indication for monoclonal antibodies. FDA has approved Aimovig, a product of the Amgen and Novartis Neuroscience Collaboration, for the prevention of frequent, debilitating migraines.  Aimovig is a human immunoglobulin G2 monoclonal...

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